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Oncoinvent presents a unique opportunity to join an expanding pharmaceutical start-up with both R&D and production established in-house which enables both hands-on lab work as well as working with external partners.

The company has solid owners and is in a clinical phase with its lead product (Radspherin®) which is produced in Nydalen.

The candidates should be looking for the energy in a start up with the ambition to make a difference. Successful candidates should be flexible, team-oriented yet able to work independently, and be analytical and results oriented.

If you would like to send us an open application, please send your application and résumé to info@oncoinvent.com

Vacancies:

Research Scientist, radionuclide therapies

Oncoinvent AS is looking for a Research Scientist to strengthen the Research and Development team at the laboratory facility in Oslo. Today the R&D team consists of seven research scientists and PhD students. The position is an exciting opportunity to work in an innovative and dynamic company and participate in the development of novel pharmaceuticals.

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Production Scientists

Oncoinvent AS is looking for scientists to strengthen the production team at the manufacturing facility in Oslo. The production team at Oncoinvent is tasked with the development and GMP compliant production of radiopharmaceuticals. This is an exciting opportunity to work in an innovative and dynamic start-up company and participate in the development of novel pharmaceuticals that helps patients worldwide.

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Oncoinvent AS Gullhaugveien 7 0484 Oslo Norway

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Research Scientist - radionuclide therapies

Oncoinvent AS is looking for a Research Scientist to strengthen the Research and Development team at the laboratory facility in Oslo. Today the R&D team consists of seven research scientists and PhD students. The position is an exciting opportunity to work in an innovative and dynamic company and participate in the development of novel pharmaceuticals.

The research scientist will be working with developments and testing of targeted alpha therapy candidates for treatment of cancer. The position is in the team that develops the pipeline products of Oncoinvent and will have responsibilities within radionuclide developments.

The company prides itself with an inclusive working environment with a shared vision, in new modern facilities in Nydalen in Oslo, close to the sub way station.

Key responsibilities:

Perform Laboratory experiments related to development of radiopharmaceutical products
Participate in development of process for radionuclide preparation, perform extractions, labelings, measurements
Assist in planning and performing analyses and research experiments
Record, analyse and communicate results of experiments
Write and review experimental protocols and reports
Organize data and results
Troubleshooting of experimental design and analytical methods
Maintain and troubleshoot analytical instrumentation as needed
Writing of SOPs and other instructional documents
The position requires work with radioactive materials. It is therefore important to comply with radiation protection and other health and safety procedures during laboratory experiments.

Qualifications and experience:

The holder of this position should have the following documented qualifications and experience:

Sc. in radiochemistry, chemistry, analytical chemistry or biotechnology
2-5 years relevant work experience in radiochemistry and/chemistry, with preparation and testing of radiopharmaceutical candidates would be preferred
Working knowledge in Norwegian and English.
A successful candidate should enjoy working in a multidisciplinary team displaying a systematic and analytical approach while being able to plan and perform tasks completing them on time. The candidate should be curious of nature and display an innovative behaviour.

Location

The holder of this position will be based at Oncoinvent AS facilities, Gullhaugveien 7, 0484 Oslo. The position will report to the Chief Scientific Officer.

About Oncoinvent

Oncoinvent is a privately held Norwegian company based in Nydalen, Oslo. The company is committed to developing novel, innovative products to provide better treatment options for cancer patients.

The Oncoinvent team consists of 40 employees and the company anticipates further growth.

Oncoinvent holds a state-of-the-art manufacturing facility to produce drug product intended for use in pre-clinical and clinical trials. Clinical trials for Oncoinvent’s lead product, Radspherin® are ongoing. For further details on Oncoinvent see www.oncoinvent.com.

The facility holds a GMP certificate from the Norwegian Medical Agency. The approval provides the company with the necessary flexibility and capacity for manufacturing clinical trial material for both patients and trial sites, as well as developing the company further.

The company’s lead product candidate Radspherin^® is a novel alpha-emitting radioactive microsphere suspension designed for treatment of micro-metastatic cancers in body cavities. The radium-224 based therapeutic, Radspherin^® has shown strong and consistent anticancer activity at doses being essentially non-toxic in preclinical studies. It is anticipated that the product can potentially treat several forms of micro-metastatic cancer.

The development programs of the pipeline of the company include targeted radionuclide therapy for treatment of various solid cancers. The main focus of discovery is on alpha-emitting radionuclides for treatment by regional administration of the drug in body compartments with disseminated solid tumors.

Application deadline: NA

Please submit your application with a motivational letter stating “why Oncoinvent” and what you can contribute to the position as well as an updated CV. Application without this will not be reviewed further.

Contact

Bjørn Fuglaas, 90775752

Production Scientist

Oncoinvent is a privately held Norwegian company based in Nydalen, Oslo. The company is committed to developing novel, innovative products to provide better treatment options for cancer patients.

The Oncoinvent team consists of 40 employees and the company anticipates further growth. Oncoinvent holds a state-of-the-art manufacturing facility to produce drug product intended for use in pre-clinical and clinical trials. Clinical trials for Oncoinvent’s lead product, Radspherin® are ongoing. For further details on Oncoinvent see www.oncoinvent.com.

The facility holds a GMP certificate from the Norwegian Medical Agency. The approval provides the company with the necessary flexibility and capacity for manufacturing clinical trial material for both patients and trial sites, as well as developing the company further.

The company’s lead product candidate Radspherin® is a novel alpha-emitting radioactive microsphere suspension designed for treatment of micro-metastatic cancers in body cavities. The radium-224 based therapeutic, Radspherin® has shown strong and consistent anticancer activity at doses being essentially non-toxic in preclinical studies. It is anticipated that the product can potentially treat several forms of micro-metastatic cancer.

The development programs of the pipeline of the company include targeted radionuclide therapy for treatment of various solid cancers. The main focus of discovery is on alpha-emitting radionuclides for treatment by regional administration of the drug in body compartments with disseminated solid tumours.

Description

Oncoinvent AS is looking for scientists to strengthen the production team at the manufacturing facility in Oslo. The production team at Oncoinvent is tasked with the development and GMP compliant production of radiopharmaceuticals. This is an exciting opportunity to work in an innovative and dynamic start-up company and participate in the development of novel pharmaceuticals that helps patients worldwide.

The successful candidates will, together with the production team and other Oncoinvent staff, drive the manufacture and development of Radspherin^® for pre-clinical and early-phase clinical trials.

These positions requires work with radioactive materials. The successful candidates are therefore expected to comply with radiation protection and other health and safety procedures during laboratory- and production scale experiments, and GMP production activities.

Key responsibilities:

Routine, GMP compliant production of radium-224, calcium carbonate microparticles and Radspherin^® to supply clinical trials.
Planning, designing and conducting laboratory- and production scale experiments with the aim of increasing the yield and scale of the Ra-224 drug substance and Radspherin^® processes.
Support the production- and R&D team during the development of new manufacturing processes and debottlenecking of existing processes, incl. troubleshooting of technical challenges.
Write and review experimental protocols and reports. Document experimental procedures and results according to GLP and GMP guidelines.
Write and review batch manufacturing records. Produce and document the production of pre-clinical and clinical drug product according to GMP.
Review and analyze results from laboratory- and production scale experiments. Communicate results and findings to Oncoinvent’s staff and management team.
Develop and maintain a working knowledge in Good Manufacturing Practice (GMP) and participate in annual GMP training.
Help with maintaining the calibration and qualification status of Oncoinvent’s production facility, equipment and instruments.
Support production, QC and QA in the investigation and closure of any deviations. Aid production, QC and QA in the implementation of Corrective and Preventative Actions (CAPA).
If necessary, support and participate in internal audits and audits performed external, national or international regulatory bodies.
Housekeeping and routine cleaning of GMP production rooms and general laboratory, including handling of radioactive and non-active waste.
Support the production- and R&D team during the development of Oncoinvent’s product pipe-line.

Qualifications and experience:

The candidates for this position should have the following documented qualifications and experience:

Sc. in chemical engineering, process chemistry or other relevant discipline.
1-3 years practical, hands-on experience in development and production of pharmaceuticals.
Working knowledge in Norwegian and English.
Familiarity with cGMP regulation and experience with working in clean rooms is an advantage.
The production of pharmaceutical is highly regulated, and a successful candidate will be expected to show a high attention to detail with respect to planning and documentation of practical work.
Experience in solid-liquid separation and/or production of colloids and/or radiochemistry is an advantage.
A successful candidate will further have to be able to work in a multidisciplinary team, have a systematic and analytical approach with sound judgement while being able to plan and perform practical work independently.

Location
These positions will be based at Oncoinvent AS, Gullhaugveien 7, 0484 Oslo. The position will report to the Head of Production.

Contact:

Please submit your written application describing why Oncoinvent and what you can contribute. Any questions – please feel free to reach out to Bjørn Fuglaas at Gevirgroup AS (+47 90775752) for a confidential discussion.